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Research Trends in Cell Biology Education
Horníček, Jan ; Vojíř, Karel (advisor) ; Pavlasová, Lenka (referee)
Cell biology is a scientific field that brings concepts, the knowledge of which is a essential for understanding the laws of life.It focuses on studying the cell as a fundamental building and functioning unit composing all living organisms For this reason, this bachelor thesis focuses on articles that analyze the didactics of cell biology and were published in the Web of Science database between 2018 and 2022. A total of 53 articles were selected. However, 28 of them were scientifically advanced texts that were not related to education. A total of 25 articles that dealt with the didactics of cell biology were analyzed. The main topics of those articles that were analyzed were teaching methods, misconceptions in cell biology, laboratory methods and procedures, visualization of cell biology topics, alternative classification systems, distance learning, concept maps, inquiry-based learning, role-playing, and cell biology topics projected into practice. The main conclusion is that the articles primarily focus on the tertiary level of education. Only marginally, 2 of the articles mention teaching at the secondary level of education. Misconceptions in cell biology are not represented in large numbers and truly new teaching methods are not represented. It would be useful to expand the database of...
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Pentoses as energy sources of Mastigamoeba balamuthi
Novotná, Monika ; Verner, Zdeněk (advisor) ; Čepička, Ivan (referee)
Mastigamoeba balamuthi is a free-living amoeba, a sister group to one of the most widespread parasitic agent Entamoeba histolytica. During its lifetime, M. balamuthi can utilize at least four different energy sources to produce ATP. In addition to glucose, a standard cultivation energy source, the amoeba can utilize pentoses xylose and arabinose, as well as an amino acid L-arginine. In this work, energy source preference was assessed. Morphological and physiological characteristics including cell growth and size, motility, number of nuclei and metabolic end products were evaluated. It was concluded that glucose appears to be a less preferred energy source than pentose upon evaluating statistically significant differences. Therefore, it was proposed to replace the commonly used hexose with the preferred xylose in the culture medium of M. balamuthi.
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The Development of the Original Didactic Game "A Journey to the Cell"
Strachotová, Tereza ; Dvořáková, Radka (advisor) ; Chlebounová, Irena (referee)
Cell biology is a rapidly developing complex field of science, the basics of which students in the second grade of elementary school often come into contact within the sixth grade. Due to the difficulty, the curriculum is often abbreviated, which can be confusing for students in later years. Since the subject matter is abstract, many students have problems understanding it. The goal of this diploma thesis was to create a didactic board game focused on the construction of an animal cell, which will serve as teaching material primarily in the 6th year of elementary school. The game was gradually modified in such a way as to best help fulfill the set didactic goals of the game: the student assigns functions to cell organelles, the student finds the learning activity fun, the student cooperates with others to solve a certain problem and helps to reach a common goal. Throughout the game, the pupils get to know the construction of a cell on a wider scale than is usually the case in primary schools. They work together in a group, travel through the cell and collect building materials, for which they get cards with organelles. While playing the game, they discover that the cell contains a large number of parts, each of which has a clear role in the life of the cell. Students will learn more about the...
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Cell Biology in Czech Lower-secondary Biology Textbooks
Zupko, Jakub ; Dvořáková, Radka (advisor) ; Kuba, Radim (referee)
Cell biology is a dynamic but also complex and abstract scientific field. Therefore, it is crucial that teachers have sufficient quality teaching material to teach it. This paper aims to assess the quality of the cell biology chapters in five Czech textbooks for 6th-grade science. Specifically, the textbooks of Fraus, Nová Škola, Prodos, SPN and Taktik publishers are the set under study. The content analysis of the textbooks focuses on six aspects: scope of the material, terminology, difficulty of the explanatory text (measured by the Hrabí method), content accuracy, the cognitive difficulty of the accompanying tasks (according to Bloom's taxonomy) and the nature of the non- verbal component of the textbooks. Differences were found in the didactic equipment and the correctness of the content of individual textbooks. In four of the five explanatory texts it is possible to find incorrect information (at least three and at most twelve false statements). Most of the accompanying tasks are aimed at the lowest levels of Bloom's taxonomy. The nonverbal component on average occupies almost one-third of the page space, with the most common type of pictorial component being a sketch. The most suitable textbook, based on the examined criteria, is the textbook published by SPN, followed by the textbook...
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Applications of Machine Learning for Detecting and Counting Objects in Cell Biology
Brázdilová, Květa ; Stopka, Pavel (advisor) ; Hoksza, David (referee)
Modern biological research generates large amounts of data, which require automation for efficient analysis. Lately, machine learning solutions are being developed for many of the problems in this field. This thesis focuses on applications of machine learning for image analysis, such as detecting cells in microscopy images and classifying them based on their phenotype. After a brief introduction to machine learning concepts, eight published methods are presented, which employ machine learning for either detecting and classifying, or counting objects in biological images. Five open-source software tools for biological image analysis, which employ some of the methods mentioned above, are introduced. A new project is also described, which aims to create a convolutional neural network for counting bacterial colonies in images of agar plates. The results of this project are discussed. Keywords: machine learning, neural network, pattern recognition, cell biology, segmentation
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The Cell Biology - teaching portfolio for educational thematic area of biology for high school
VEJDĚLKOVÁ, Zdeňka
The goal of the diploma thesis is to create a teaching portfolio for educational thematic area of the cell biology. Teaching materials are intended for high school students learning. The portfolio is aimed at the topic of cell construction. The portfolio is projected for the independent work of students. It can be used both in subject matter explanation and as home preparation. A revision test is a part of the portfolio. Activating part of the portfolio is composed of thematic games that are suitable for the subject matter revision and deepening of knowledge.
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Practical exercises in cell biology curriculum for grammar schools
MANDRYSZOVÁ, Jana
This diploma thesis contains a collection of 29 practical exercises, aimed at cell biology. These excercises were developed on analysis of cell biology curriculum in Framework Education Programme for grammar schools, available biology textbooks and professional literature based on this topic. Practical exercises follow up active and inquiry-based approach of students to biology education. The execises include protocol suggestions for exercises, education goals summary, methodical notes for teachers and model answers.
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